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syllabus
Section
1
hOMEWORK
See Lecture Notes
Handouts
None at this time
Problems
Protein MW
Protein Sequencing
Lectures
Chapter 1
Chapter 2
Chapter 3
(4
per page)
Chapter 4
(4
per page)
Chapter 5
(4
per page)
Chapter 6 (4
per page)
Chapter 7
(4
per page)
Chapter 8
(4
per page)
Chapter
9 (4
per page)
Chapter 10 (4
per page)
Chapter 11
(4
per page)
Chapter 12
(4
per page)
Chapter 13
(4 per
page)
Chapter
14 (4
per page)
Chapter 15 (4
per page)
Chapter 16 (4
per page)
Chapter 17 (4
per page)
Chapter 18 (4 per page)
Chapter 19 (4 per page)
Chapter 21 (4 per page)
Chapter 23 (4 per page)
Chapter 24 (4 per page)
Chapter 25 (4 per page)
Chapter 26 (4 per page)
Chapter 27 (4 per page)
Chapter 28 (4 per page)
Biochem Sites
Companies:
http://www.sigmaaldrich.com
http://www.piercenet.com
http://www.fishersci.com
http://www.neb.com
http://www.invitrogen.com
http://www.biorad.com
NIH Genome Project:
http://www.genome.gov/
NCBI:
http://www.ncbi.nlm.nih.gov/
Protein Data Bank:
http://www.rcsb.org/pdb/
Swiss-Prot:
http://us.expasy.org/sprot/
GeneAtlas:
http://www.dsi.univ-paris5.fr/genatlas/
GeneTests:
http://www.genetests.org/
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CHE 422 is a one-semester course that extends the foundational
biochemistry knowledge gained in CHE 421. Bioenergetics and metabolic
processes and their regulation are explored as well as biological
information pathways. Further study focuses on exploration of current
topics, particularly those related to the biochemistry of proteins and
nucleic acids. Critical reading of the biochemical literature acquaints
students with modern experimental methods and familiarizes them with
current advances in this fascinating field.
Students who apply themselves and master the material
covered in Chemistry 422 will:
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Build upon foundational
knowledge of biochemistry established in CHE 421.
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Know the major metabolic
pathways of amino acids, sugars, and lipids and the means by which
these pathways are regulated.
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Examine roles of proteins and
nucleic acids in DNA-based information technologies and eukaryotic
information pathways including regulation of metabolism and gene
expression.
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Learn how to critically read
scientific literature to learn about a topic and to explore research
questions.
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Understand the principal
laboratory techniques used to investigate living processes, and to
consider how they may be applied to seek answers to biochemical
research questions.
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Appreciate the relationship
between the biochemical process of the cell and the etiology of
disease.
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Complete an individual research
project by consulting recent literature articles, and present a
summary of findings to the class audience.
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Have an increased awareness of
how the scientific community communicates and disseminates research
findings by gaining familiarity with journal articles and public
databases.
Suggestions
for Success in CHE 422:
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Personally engage in
the learning process: pay attention, ask questions, think.
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Ask for help. It’s
free and freely given. In addition to asking questions in class and
during office hours, departmental tutors are available for a nominal
fee.
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Form a study group.
However, maintain individual responsibility for your learning and don’t
assume that because peers know the material you do.
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Read textbook
material before lectures.
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Review and rewrite
lecture notes after class
and keep a list of questions to ask. Clear up
any confusion early and refresh key ideas.
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Keep up with reading
and homework assignments. This course follows a demanding pace. Falling
behind will be disastrous. As a general guideline, plan to spend around
3 hours of study time for every hour of lecture (approx. 9 hours/week).
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Check the answers to
homework problems and learn from your mistakes. Get in the habit of
conceptually questioning your answers (“does this make sense?”).
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Try to connect
material of the course to other things: life, core courses, the news,
pleasure reading, etc. Share your insights with others. I welcome
contributions of this nature during class
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